SS-31 10MG

🧬 SS-31 (Elamipretide) | Mitochondrial Bioenergetic Peptide

SS-31, also known as Elamipretide, is a mitochondria-targeting tetrapeptide designed to support mitochondrial structure, optimize energy output, and reduce oxidative stress. Research models and preclinical studies highlight its broad potential in addressing cellular dysfunction driven by mitochondrial decline.

⚙️ Mechanism of Action: Precision Targeting of Mitochondria

SS-31 exhibits its bioactivity by localizing to the inner mitochondrial membrane, where it binds to cardiolipin — a phospholipid critical for mitochondrial stability and function. By stabilizing cardiolipin, SS-31 helps preserve the shape and integrity of mitochondrial cristae, optimizing the organelle’s ability to produce energy.

🧲 Key Actions in Research Models:

• Preserves mitochondrial architecture
• Reduces ROS (reactive oxygen species)
• Enhances electron transport chain efficiency
• Boosts ATP synthesis
• Inhibits mitochondrial-driven apoptosis

🔋 SS-31 & Mitochondrial Dysfunction

Mitochondria are central to cellular energy and resilience. Dysfunction at this level can trigger cascading issues across organ systems. SS-31 has demonstrated potential in restoring mitochondrial structure and bioenergetics:

• Restores mitochondrial length and cristae integrity
• Improves ATP production and reduces oxidative damage
• Supports mitochondrial dynamics in models of kidney disease and cardiomyopathy

🧠 Neuroprotection & Cognitive Support

In models of inflammation-induced cognitive decline, SS-31 improved mitochondrial function and cognitive performance, showing potential in research focused on age-related brain changes and neuroinflammation.

🧬 Renal Support: Kidney Bioenergetics

SS-31 has shown renoprotective effects in kidney-related studies by:

• Reducing markers of inflammation and oxidative stress
• Decreasing proteinuria and podocyte loss
• Preserving glomerular structure and function

❤️ Cardiac Bioenergetics & Barth Syndrome

In cardiac models, SS-31 has improved mitochondrial efficiency, reduced ROS, and enhanced overall cardiac performance. Notably, in Barth Syndrome, it has:

• Improved muscle strength and exercise capacity
• Supported cardiac metrics through mitochondrial stabilization

🔥 Cachexia & Muscle Wasting (Cancer Models)

SS-31 has shown promise in:

• Mitigating muscle degradation and fatigue
• Preserving energy metabolism in cachexia
• Supporting muscle energetics without affecting tumor burden

🧯 Oxidative Stress, Autophagy & PAD

SS-31 aids in restoring autophagic flux, protecting against muscle ischemia in aging models. It:

• Enhances skeletal muscle structure
• Reduces oxidative stress
• Shows therapeutic potential in Peripheral Artery Disease (PAD)

🩸 SS-31 in Metabolic Research (T2D)

SS-31 has demonstrated the ability to:

• Elevate SIRT1 levels
• Reduce systemic inflammation and oxidative load
• Improve vascular health and mitochondrial resilience in type 2 diabetes models

⚠️ Research Use Only Notice:

This product is sold strictly for laboratory research purposes only. It is not for human or animal use, and not for therapeutic or diagnostic applications.

By purchasing, you confirm that you are a qualified individual using this product in accordance with all applicable laws and research regulations.